Stroke victims who have obstructive sleep apnea die sooner than stroke victims who do not have sleep apnea or who have central sleep apnea, according to Swedish researchers, who will present their findings at the American Thoracic Society’s 2008 International Conference in Toronto on Monday, May 19.
The researchers followed 132 stroke patients over 10 years. Twenty-three of those patients had obstructive sleep apnea; 28 of those patients had central sleep apnea. Those with an obstructive apnea-hypopnea index of 15 or greater were 76 percent more likely to die earlier. Those with a lower apnea-hypopnea index of 10 were also at greater risk of early death.
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Research findings presented at Sleep 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, a link exists between the severity of obstructive sleep apnea (OSA) and weight gain.
Results indicate that people with an apnea-hypopnea index (AHI), the average of the combined episodes of apnea and hypopnea that occur per hour of sleep, of over 15 had an increase in body mass index (BMI) of 0.52 kg/m2 compared to those with an AHI between five and 15, who saw an increase of 0.22 kg/m2.
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Individuals with sleep-related breathing disorders appear to burn more calories when resting as their conditions become more severe, according to a report in Archives of Otolaryngology–Head & Neck Surgery.
Sleep-related breathing disorders include snoring, sleep apnea, and other conditions in which airways are partially or completely obstructed during sleep. “Obesity is a major risk factor for the development of sleep-disordered breathing, and changes in body weight are associated with changes in sleep-disordered breathing severity,” the authors wrote.
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A study published in the July 1, 2008, issue of the journal Sleep provides visual evidence of the severe structural damage that occurs in numerous regions of the brain in people with obstructive sleep apnea (OSA).
Results show that obstructive sleep apnea patients have extensive alterations in “white matter,” nerve tissue in the brain containing fibers that are insulated with myelin — a white, fatty sheath. These structural changes appear both in brain regions that have functional importance for characteristics such as mood, memory, and cardiovascular regulation; and in fiber pathways interconnecting these regions.
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Prescription sleep aids may do little to improve the use of continuous positive airway pressure devices (CPAP) among patients with obstructive sleep apnea (OSA).
A new study published in the November issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), finds that patients with OSA who were given prescription sleep aids were no more likely to use their CPAP machines than patients with obstructive sleep apnea taking a placebo.
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