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Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in JAMA.
Modafinil, a wake-promoting drug used to treat sleep disorders, may enhance cognition and is used off-label for the treatment of cognitive dysfunction in some psychiatric disorders, such as schizophrenia and attention-deficit/hyperactivity disorder (ADHD).
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Vanda, Pharmaceuticals, Proof-of-Concept, Phase II, clinical testing, VSF-173, excessive sleepiness, maintenance of wakefulness tests, MWT, modafinil, Provigil, Nuvigil, narcolepsy, polysomnography, PSG, Mihael Polymeropoulos, shift work sleep disorder, neuro-degenerative disorders, sleep disorders, sleepiness, excessive sleepiness, problem sleepiness.
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